Publications

Scientific Output

Explore our peer-reviewed publications, research papers, and academic contributions advancing the understanding of child health through comprehensive longitudinal studies and evidence-based research.

2024

December 11, 2024

Incidental and Progressive Tobacco Smoking in Childhood and Subsequent Risk of Premature Cardiac Damage

Agbaje, Andrew O

Journal of the American College of Cardiology

Original article cardiac-health
November 13, 2024

Lean Mass Longitudinally Confounds Sedentary Time and Physical Activity With Blood Pressure Progression in 2513 Children

Agbaje, Andrew O

Journal of cachexia, sarcopenia and muscle , 1-16

Original article physical-activity
November 11, 2024

Incidental and progressive tobacco smoking from childhood through young adulthood with premature structural and functional cardiac damage in 1931 children: A 14-Year Longitudinal Study

Agbaje, Andrew O

Circulation , 150 , Supplement_1

Conference abstract cardiac-health
November 1, 2024

JHH Young Investigator Award 2023: interview with the winner Andrew O. Agbaje

Agbaje, Andrew O

Journal of Human Hypertension , 38 , 733-735

Original article research-recognition
October 29, 2024

Effectiveness of a school-based high-intensity interval training intervention in adolescents: study protocol of the PRO-HIIT cluster randomised controlled trial

Liu, Yong; Barker, Alan R; Adlam, Anna-Lynne R.; Li, Minghui; Duncombe, Stephanie L.; Agbaje, Andrew O.; Gu, Yaodong; Zhou, Huiyu; Williams, Craig A.

Frontiers in pediatrics , 12 , . 1458610

Study protocol physical-activity
October 29, 2024

JHH Young Investigator Award 2023: interview with the winner Andrew O. Agbaje

Agbaje, Andrew O

Journal of human hypertension , 38 , 733-735

research-recognition
October 1, 2024

Fat mass mediating effect on the association of worsening insulin resistance with increased left ventricular mass in 1595 adolescents: a 7-Year Longitudinal and Mediation Study

Agbaje, Andrew O

European Heart Journal

Conference abstract metabolic-health
June 13, 2024

Increased low-density lipoprotein cholesterol predict the risk of progressive structural but not functional cardiac damage in youth: a 7-year follow-up study

Agbaje, Andrew O

European journal of preventive cardiology

Conference abstract cardiac-health
June 13, 2024

No association between increased high-density lipoprotein cholesterol and progressive cardiac damage in 1595 adolescents: a 7-year longitudinal study

Agbaje, Andrew O

European journal of preventive cardiology

Conference abstract cardiac-health
June 12, 2024

Author reply to correspondence from Hudda et al. on waist-circumference-to-height-ratio had better longitudinal agreement with DEXA-measured fat mass than BMI in 7237 children

Agbaje, Andrew O

Pediatric research , 1-2

Correspondence research-response
May 29, 2024

Accelerometer-based sedentary time and physical activity with MASLD and liver cirrhosis in 2684 British adolescents

Agbaje, Andrew O

npj gut and liver , 1 , 1-13

Study protocol liver-health
May 7, 2024

Accelerometer-based sedentary time and physical activity from childhood through young adulthood with progressive cardiac changes: a 13-year longitudinal study

Agbaje, Andrew O

European journal of preventive cardiology , 31 , 1480-1492

Study protocol cardiac-health
April 15, 2024

Environmental Exposures and Pediatric Cardiology: A Scientific Statement From the American Heart Association

Zachariah, Justin P; Jone, Pei-Ni; Agbaje, Andrew O; Ryan, Heather H; Trasande, Leonardo; Perng, Wei; Farzan, Shohreh F; on behalf of the American Heart Association Council on Lifelong Congenital Heart and Heart Health in the Young; Council on Cardiovascular and Stroke Nursing; Council on Epidemiology and Prevention; Council on Lifestyle and Cardiometabolic Health; and Council on Clinical Cardiology

Circulation , 149 , e1165-e1175

Review cardiovascular-health
March 21, 2024

Accelerometerโ€based sedentary time, light physical activity, and moderateโ€toโ€vigorous physical activity from childhood with arterial stiffness and carotid IMT progression: A 13โ€year longitudinal study of 1339 children

Agbaje, Andrew O; Barker, Alan R; Lewandowski, Adam J; Leeson, Paul; Tuomainen, Tomiโ€Pekka

Acta physiologica , 240

Study protocol cardiovascular-health
March 5, 2024

Waist-circumference-to-height-ratio had better longitudinal agreement with DEXA-measured fat mass than BMI in 7237 children

Agbaje, Andrew O

Pediatric research , 1-12

Study protocol physical-measurements
March 1, 2024

The Interactive Effects of Sedentary Time, Physical Activity, and Fat Mass on Insulin Resistance in the Young Population

Agbaje, Andrew O

The Journal of Clinical Endocrinology and Metabolism

Original article metabolic-health
February 26, 2024

Mediating effect of fat mass, lean mass, blood pressure and insulin resistance on the associations of accelerometer-based sedentary time and physical activity with arterial stiffness, carotid IMT and carotid elasticity in 1574 adolescents

Agbaje, Andrew O

Journal of human hypertension , 38 , 393-403

Study protocol cardiovascular-health
February 1, 2024

Increasing lipids with risk of worsening cardiac damage in 1595 adolescents: A 7-year longitudinal and mediation study

Agbaje, Andrew O

Atherosclerosis , 389

Study protocol cardiovascular-health
January 6, 2024

DXA-based Fat Mass With Risk of Worsening Insulin Resistance in Adolescents: A 9-Year Temporal and Mediation Study

Agbaje, Andrew O; Saner, Christoph; Zhang, Jie; Henderson, Mรฉlanie; Tuomainen, Tomi-Pekka

Journal of clinical endocrinology and metabolism , 109 , e1708-e1719

Study protocol metabolic-health
January 1, 2024

Inflammation: reviewing current evidence

Agbaje, Andrew O

TYร–TERVEYSLร„ร„Kร„RI , 42 , 44-47

inflammation

2023

December 14, 2023

Associations of Sedentary Time and Physical Activity From Childhood With Lipids: A 13-Year Mediation and Temporal Study

Agbaje, Andrew O

Journal of clinical endocrinology and metabolism , 109 , e1494-e1505

Study protocol physical-activity
December 12, 2023

Effects of accelerometer-based sedentary time and physical activity on DEXA-measured fat mass in 6059 children

Agbaje, Andrew O; Perng, Wei; Tuomainen, Tomi Pekka

Nature communications , 14

Study protocol physical-activity
December 12, 2023

Longitudinal Mediating Effect of Fat Mass and Lipids on Sedentary Time, Light PA, and MVPA with Inflammation in Youth

Agbaje, Andrew O

Journal of clinical endocrinology and metabolism , 108 , 3250-3259

Study protocol metabolic-health
November 9, 2023

A 7-year longitudinal association of total cholesterol with premature structural and functional cardiac damage progression in youth: the ALSPAC birth cohort study

Agbaje, Andrew O

European heart journal

Conference abstract cardiovascular-health
November 9, 2023

An average of 60mins/day of moderate to vigorous physical activity from childhood through young adulthood was associated with worsening cardiac structural damage in youth: A 13-year longitudinal study

Agbaje, Andrew O

European heart journal abstract

Study protocol physical-activity
November 9, 2023

Cumulative accelerometer-based light physical activity from childhood through young adulthood progressively decreases left ventricular mass in British youth: a 13-year longitudinal study

Agbaje, Andrew O

European heart journal

physical-activity
November 9, 2023

Cumulative accelerometer-based light physical activity from childhood through young adulthood with arterial stiffness and carotid intima-media thickness progression: a 13-year longitudinal study

Agbaje, Andrew O; Barker, Anna; Lewandowski, Adam James; Leeson, Paul; Tuomainen, Tomi-Pekka

European heart journal

physical-activity
November 9, 2023

Cumulative accelerometer-based sedentary time from childhood through young adulthood with increased arterial stiffness and carotid intima-media thickness in youth: a 13-year longitudinal study

Agbaje, Andrew O; Barker, Anna; Lewandowski, Adam James; Leeson, Paul; Tuomainen, Tomi-Pekka

European heart journal

physical-activity
November 9, 2023

Cumulative accelerometer-based sedentary time from childhood through young adulthood with progressive left ventricular remodelling in British youth: a 13-year longitudinal study

Agbaje, Andrew O

European heart journal

physical-activity
November 9, 2023

Increased triglyceride independently associates with premature structural and functional cardiac damage progression in asymptomatic adolescents: a 7-year longitudinal study

Agbaje, Andrew O

European heart journal

cardiovascular-health
November 9, 2023

Prospective associations of non-HDL cholesterol with premature structural and functional cardiac damage progression in British youth: the ALSPAC study

Agbaje, Andrew O

European heart journal

cardiovascular-health
November 6, 2023

Longitudinal Associations of Accelerometer-Based Sedentary Time and Physical Activity With Blood Pressure Progression From Childhood Through Young Adulthood: A 13-year Mediation and Isotemporal Substitution Study of 2513 Children

Agbaje, Andrew O

Circulation

physical-activity
September 11, 2023

Arterial stiffness but not carotid intima-media thickness progression precedes premature structural and functional cardiac damage in youth: A 7-year temporal and mediation longitudinal study

Agbaje, Andrew O; Zachariah, Justin P; Tuomainen, Tomi-Pekka.

Atherosclerosis , 380

Study protocol cardiovascular-health
August 11, 2023

Suppressing effect of HDL-cholesterol on the associations of accelerometer-based sedentary time with low-grade inflammation: A 13-year longitudinal study from childhood through young adulthood

Agbaje, Andrew O

Atherosclerosis

cardiovascular-health
August 1, 2023

Cumulative effect of accelerometer-based moderate-to-vigorous physical activity from childhood through young adulthood on carotid intima-media thickness progression: The ALSPAC birth cohort study

Agbaje, Andrew O

Atherosclerosis

physical-activity
June 28, 2023

Adolescents cholesterol passport: a universal pediatric lipid screening tool to combat atherosclerosisโ€”the world's deadliest scourge

Agbaje, Andrew O

Frontiers in pediatrics , 11

cardiovascular-health
June 28, 2023

Adolescents cholesterol passport: a universal pediatric lipid screening tool to combat atherosclerosisโ€”the world's deadliest scourge

Agbaje, Andrew O

Frontiers in pediatrics , 11 , . 1228483

Study protocol cardiovascular-health
May 17, 2023

Arterial Stiffness Preceding Metabolic Syndrome in 3862 Adolescents: A Mediation and Temporal Causal Longitudinal Birth Cohort Study

Agbaje, Andrew O

American journal of physiology : heart and circulatory physiology , 324 , H905-H911

Study protocol cardiovascular-health
April 25, 2023

Does arterial stiffness mediate or suppress the associations of blood pressure with cardiac structure and function in adolescents?

Agbaje, Andrew O

American journal of physiology : heart and circulatory physiology , 324 , H776-H781

Study protocol cardiovascular-health
April 10, 2023

Associations of accelerometerโ€based sedentary time, light physical activity, and moderateโ€toโ€vigorous physical activity with resting cardiac structure and function in adolescents according to sex, fat mass, lean mass, BMI, and hypertensive status

Agbaje, Andrew O

Scandinavian journal of medicine and science in sports , 33 , 1399-1411

Study protocol physical-activity
March 23, 2023

Longitudinal Left Ventricular Mass Indexing for DEXA-Measured Lean Mass and Fat Mass: Normative Reference Centiles in Post-Pubertal Adolescents and Young Adults

Agbaje, Andrew O

American journal of physiology : heart and circulatory physiology , 324 , H571-H577

Study protocol cardiovascular-health
March 10, 2023

Cumulative insulin resistance and hyperglycaemia with arterial stiffness and carotid IMT progression in 1779 adolescents: A 9-Year Longitudinal Cohort Study

Agbaje, Andrew O; Zachariah, Justin P; Bamsa, Olutola; Odili, Augustine N; Tuomainen, Tomi-Pekka

American journal of physiology : endocrinology and metabolism , 324 , E268-E278

Study protocol metabolic-health
March 10, 2023

Temporal longitudinal associations of carotid-femoral pulse wave velocity and carotid intima-media thickness with resting heart rate and inflammation in youth

Agbaje, Andrew O; Barmi, Samuel; Sansum, Kate M; Baynard, Tracy; Barker, Alan R; Tuomainen, Tomi-Pekka

Journal of applied physiology , 134 , 657-666

Study protocol cardiovascular-health
March 2, 2023

Elevated Blood Pressure and Worsening Cardiac Damage During Adolescence

Agbaje, Andrew O

Journal of pediatrics , 257

Study protocol cardiac-health
January 1, 2023

Cumulative dyslipidemia with arterial stiffness and carotid IMT progression in asymptomatic adolescents: A simulated intervention longitudinal study using temporal inverse allocation model

Agbaje, Andrew O.; Lloyd-Jones, Donald M.; Magnussen, Costan G.; Tuomainen, Tomi-Pekka

Atherosclerosis , 364 , 39-48

Study protocol cardiovascular-health

2022

December 13, 2022

Cardiorespiratory Fitness in Adolescence: A Telescope into Future Cardiovascular Health

Agbaje, Andrew O

European journal of preventive cardiology , 30 , 404-406

Editorial physical-activity
October 14, 2022

Cumulative muscle mass and blood pressure but not fat mass drives arterial stiffness and carotid intima-media thickness progression in the young population and is unrelated to vascular organ damage

Agbaje, Andrew O.; Barker, Alan R.; Tuomainen, Tomi-Pekka

Hypertension research , 46 , 984-999

Study protocol cardiovascular-health
October 10, 2022

To prevent hypertension in Africans: do we need to eat more vegetables?

Agbaje, Andrew O

European journal of preventive cardiology , 29 , 2333โ€“2335

Editorial cardiovascular-health
October 3, 2022

Cumulative dyslipidaemia from mid-adolescence through young adulthood with carotid intima-media thickness progression: a 9-year longitudinal study

Agbaje, Andrew O; Lloyd-Jones, D M; Magnussen, C G; Tuomainen, T P

European heart journal

cardiovascular-health
October 3, 2022

Cumulative hyperinsulinemia, hyperglycaemia, and insulin resistance from mid-adolescence through young adulthood with carotid intima-media thickness progression: a 9-year longitudinal study

Agbaje, Andrew O; Zachariah, J P; Bamsa, O; Odili, A N; Tuomainen, T P

European heart journal

metabolic-health
October 3, 2022

Does arterial stiffness progression temporally precede higher low-grade inflammation in adolescents? Causal longitudinal evidence using auto-regressive cross-lagged structural equation models

Agbaje, Andrew O; Barmi, S; Sansum, K M; Baynard, T; Barker, A R; Tuomainen, T P

European heart journal

inflammation
October 3, 2022

Longitudinal associations of cumulative dyslipidaemia from mid-adolescence through young adulthood with arterial stiffness progression: the ALSPAC study

Agbaje, Andrew O; Lloyd-Jones, D M; Magnussen, C G; Tuomainen, T P

European heart journal

Conference abstract cardiovascular-health
October 3, 2022

Simulated intervention and optimal timing for attenuating dyslipidaemia-related atherosclerotic progression in the young: a temporal inverse allocation analysis of the ALSPAC cohort

Agbaje, Andrew O; Lloyd-Jones, D M; Magnussen, C G; Tuomainen, T P

European heart journal

Conference abstract cardiovascular-health
October 3, 2022

Temporal causal longitudinal associations of high-sensitivity C-reactive protein with carotid intima-media thickness progression in adolescents: the ALSPAC birth cohort study

Agbaje, Andrew O; Barmi, S; Sansum, K M; Baynard, T; Barker, A R; Tuomainen, T P

European heart journal

Conference abstract inflammation
October 1, 2022

Arterial stiffness precedes hypertension and metabolic risks in youth: a review

Agbaje, Andrew O

Journal of hypertension , 40 , 1887-1896

Review cardiovascular-health
September 2, 2022

Mediating role of body composition and insulin resistance on the association of arterial stiffness with blood pressure among adolescents: The ALSPAC study

Agbaje, Andrew O

Frontiers in cardiovascular medicine , 9 , 939125

Study protocol cardiovascular-health
August 1, 2022

Cumulative dysglycemia, hyperinsulinemia and insulin resistance with arterial stiffness progression in healthy adolescents: The Avon Longitudinal Study of Parents and children (ALSPAC)

Agbaje, AO.

Atherosclerosis

metabolic-health
March 1, 2022

Adolescence arterial stiffness precedes elevated blood pressure in young adulthood: The ALSPAC birth cohort

Agbaje, Andrew O; Barker, Alan R; Tuomainen, Tomi-Pekka

Metabolism: clinical and experimental

cardiovascular-health
March 1, 2022

Fat mass paradox and carotid intima-media thickness progression: A longitudinal study from childhood through young adulthood

Agbaje, Andrew O; Barker, Alan R; Tuomainen, Tomi-Pekka

Metabolism: clinical and experimental

metabolic-health
March 1, 2022

Longitudinal and bi-directional associations of arterial stiffness with general and central fat mass from adolescence through young adulthood: The ALSPAC Study

Agbaje, Andrew O; Barker, Alan R; Tuomainen, Tomi-Pekka

Metabolism: clinical and experimental

cardiovascular-health
January 18, 2022

Effect of Arterial Stiffness and Carotid Intima-Media Thickness Progression on the Risk of Dysglycemia, Insulin Resistance, and Dyslipidemia: a Temporal Causal Longitudinal Study

Agbaje, Andrew O; Barker, Alan R; Mitchell, Gary F; Tuomainen, Tomi-Pekka

Hypertension , 79 , 667-678

Study protocol cardiovascular-health

2021

November 17, 2021

Effects of Arterial Stiffness and Carotid Intima-Media Thickness Progression on the Risk of Overweight/Obesity and Elevated Blood Pressure/Hypertension: a Cross-Lagged Cohort Study

Agbaje, Andrew O; Barker, Alan R; Tuomainen, Tomi-Pekka

Hypertension , 79 , 159-169

Study protocol cardiovascular-health
November 8, 2021

A 7-Year Arterial Stiffness and Carotid Intima-Media Thickness Progression Predict Obesity, High Lean Mass, and Incident Hypertension from Age 17.7 to 24.5 Years: the ALSPAC Study

Agbaje, Andrew O; Barker, Alan R; Tuomainen, Tomi-Pekka

Circulation , 144

Conference abstract cardiovascular-health
November 8, 2021

Differing Relations Of Arterial Stiffness And Carotid Intima-Media Thickness In Adolescence With Metabolic Risks In Young Adulthood: The ALSPAC Study

Agbaje, Andrew O; Barker, Alan R; Tuomainen, Tomi-Pekka

Circulation , 144

Conference abstract cardiovascular-health
October 14, 2021

Adiponectin and lean mass in relation to endothelial function, arterial elasticity and arterial stiffness in 9-11-year-old-the ALSPAC study

Agbaje, Andrew O; Barker, A R; Tuomainen, T-P

Pediatric diabetes

Conference abstract metabolic-health
October 14, 2021

Arterial stiffness in adolescence predicts elevated blood pressure in young adulthood: the ALSPAC study

Agbaje, Andrew O; Barker, A R; Tuomainen, T-P

European heart journal , 42

Conference abstract cardiovascular-health
September 2, 2021

Associations of endothelial function, arterial elasticity, and arterial stiffness with adiponectin and skeletal muscle mass

Agbaje, Andrew O; Barker, Alan R; Tuomainen, Tomi-Pekka

International journal of epidemiology , 50

Conference abstract cardiovascular-health
August 1, 2021

Arterial stiffness and carotid intima-media thickness in relation to cardiometabolic health in adolescence: The ALSPAC study

Agbaje, Andrew O; Barker, A R; Tuomainen, T-P

Atherosclerosis , 331

Conference abstract cardiovascular-health
May 18, 2021

A 15-year Cumulative High Exposure to Lean Mass and Blood Pressure but not Fat Mass predicts the 7-year change in Carotid-Femoral Pulse Wave Velocity and Carotid Intima-Media Thickness: The ALSPAC study

Agbaje, Andrew O; Barker, Alan R; Tuomainen, Tomi-Pekka

Circulation , 143

Conference abstract cardiovascular-health
May 11, 2021

Longitudinal associations of fat mass, lean mass, body mass index and blood pressure from childhood through young adulthood with carotid-femoral pulse wave velocity and carotid intima-media thickness at age 24.5 years

Agbaje, Andrew O; Barker, Alan R; Tuomainen, Tomi-Pekka

Journal of the american college of cardiology , 77

Conference abstract cardiovascular-health
March 1, 2021

Association of Fat Mass, Lean Mass, Body Mass Index, and Blood Pressure with Carotid-Femoral Pulse Wave Velocity and Carotid Intima-Media Thickness in Young Adults: The ALSPAC study

Agbaje, Andrew O; Barker, Alan R; Tuomainen, Tomi-Pekka

Metabolism: clinical and experimental , 116

Conference abstract cardiovascular-health
March 1, 2021

Association of carotid-femoral pulse wave velocity and carotid intima-media thickness with cardiometabolic risks among young adults: The Alspac study

Agbaje, Andrew O; Barker, A R; Tuomainen, T-P

Atherosclerosis , 331

Conference abstract cardiovascular-health
January 1, 2021

Cardiorespiratory Fitness, Fat Mass, and Cardiometabolic Health with Endothelial Function, Arterial Elasticity, and Stiffness in Children

Agbaje, Andrew O; Barker, Alan R; Tuomainen, Tomi-Pekka

Medicine and science in sports and exercise , 54 , 141-152

Study protocol physical-activity