Publications
Scientific Output
Explore our peer-reviewed publications, research papers, and academic contributions advancing the understanding of child health through comprehensive longitudinal studies and evidence-based research.
2025
Persistent Hyperglycemia and Insulin Resistance With the Risk of Worsening Cardiac Damage in Adolescents: A 7-Year Longitudinal Study of the ALSPAC Birth Cohort
Agbaje AO, Zachariah JP, Barker AR, Williams CA, Vlachopoulos D, Saner C, Tuomainen TP
Diabetes Care , 48(6) , 896-904
Novel Pediatric Waist-to-height Ratio Fat Mass Cutoff Predicts Liver Steatosis and Fibrosis Better than Body Mass Index: The NHANES
Agbaje AO
Journal of the Endocrine Society , 9(7) , bvaf079
Cross-sectional associations between physical activity and sedentary time with cardiovascular health in children from the ALSPAC study using compositional data analysis
Sansum KM, Bond B, Pulsford RM, McManus A, Agbaje AO, Skinner AM, Barker AR.
Scientific Reports
BMI triples overweight prevalence in 7600 children compared with waist-to-height ratio: The ALSPAC Study
Agbaje AO
Obesity and Endocrinology
Accelerometer-based sedentary time and physical activity with incident and progressive tobacco smoking in 2503 children: A 13-year mediation and temporal longitudinal study
Agbaje, Andrew O
Behavior Research and Therapy
2024
Incidental and Progressive Tobacco Smoking in Childhood and Subsequent Risk of Premature Cardiac Damage
Agbaje, Andrew O
Journal of the American College of Cardiology
Lean Mass Longitudinally Confounds Sedentary Time and Physical Activity With Blood Pressure Progression in 2513 Children
Agbaje, Andrew O
Journal of cachexia, sarcopenia and muscle , 1-16
Incidental and progressive tobacco smoking from childhood through young adulthood with premature structural and functional cardiac damage in 1931 children: A 14-Year Longitudinal Study
Agbaje, Andrew O
Circulation , 150 , Supplement_1
JHH Young Investigator Award 2023: interview with the winner Andrew O. Agbaje
Agbaje, Andrew O
Journal of Human Hypertension , 38 , 733-735
Effectiveness of a school-based high-intensity interval training intervention in adolescents: study protocol of the PRO-HIIT cluster randomised controlled trial
Liu, Yong; Barker, Alan R; Adlam, Anna-Lynne R.; Li, Minghui; Duncombe, Stephanie L.; Agbaje, Andrew O.; Gu, Yaodong; Zhou, Huiyu; Williams, Craig A.
Frontiers in pediatrics , 12 , . 1458610
JHH Young Investigator Award 2023: interview with the winner Andrew O. Agbaje
Agbaje, Andrew O
Journal of human hypertension , 38 , 733-735
Fat mass mediating effect on the association of worsening insulin resistance with increased left ventricular mass in 1595 adolescents: a 7-Year Longitudinal and Mediation Study
Agbaje, Andrew O
European Heart Journal
Increased low-density lipoprotein cholesterol predict the risk of progressive structural but not functional cardiac damage in youth: a 7-year follow-up study
Agbaje, Andrew O
European journal of preventive cardiology
No association between increased high-density lipoprotein cholesterol and progressive cardiac damage in 1595 adolescents: a 7-year longitudinal study
Agbaje, Andrew O
European journal of preventive cardiology
Author reply to correspondence from Hudda et al. on waist-circumference-to-height-ratio had better longitudinal agreement with DEXA-measured fat mass than BMI in 7237 children
Agbaje, Andrew O
Pediatric research , 1-2
Accelerometer-based sedentary time and physical activity with MASLD and liver cirrhosis in 2684 British adolescents
Agbaje, Andrew O
npj gut and liver , 1 , 1-13
Accelerometer-based sedentary time and physical activity from childhood through young adulthood with progressive cardiac changes: a 13-year longitudinal study
Agbaje, Andrew O
European journal of preventive cardiology , 31 , 1480-1492
Environmental Exposures and Pediatric Cardiology: A Scientific Statement From the American Heart Association
Zachariah, Justin P; Jone, Pei-Ni; Agbaje, Andrew O; Ryan, Heather H; Trasande, Leonardo; Perng, Wei; Farzan, Shohreh F; on behalf of the American Heart Association Council on Lifelong Congenital Heart and Heart Health in the Young; Council on Cardiovascular and Stroke Nursing; Council on Epidemiology and Prevention; Council on Lifestyle and Cardiometabolic Health; and Council on Clinical Cardiology
Circulation , 149 , e1165-e1175
Accelerometer‐based sedentary time, light physical activity, and moderate‐to‐vigorous physical activity from childhood with arterial stiffness and carotid IMT progression: A 13‐year longitudinal study of 1339 children
Agbaje, Andrew O; Barker, Alan R; Lewandowski, Adam J; Leeson, Paul; Tuomainen, Tomi‐Pekka
Acta physiologica , 240
Waist-circumference-to-height-ratio had better longitudinal agreement with DEXA-measured fat mass than BMI in 7237 children
Agbaje, Andrew O
Pediatric research , 1-12
The Interactive Effects of Sedentary Time, Physical Activity, and Fat Mass on Insulin Resistance in the Young Population
Agbaje, Andrew O
The Journal of Clinical Endocrinology and Metabolism
Mediating effect of fat mass, lean mass, blood pressure and insulin resistance on the associations of accelerometer-based sedentary time and physical activity with arterial stiffness, carotid IMT and carotid elasticity in 1574 adolescents
Agbaje, Andrew O
Journal of human hypertension , 38 , 393-403
Increasing lipids with risk of worsening cardiac damage in 1595 adolescents: A 7-year longitudinal and mediation study
Agbaje, Andrew O
Atherosclerosis , 389
DXA-based Fat Mass With Risk of Worsening Insulin Resistance in Adolescents: A 9-Year Temporal and Mediation Study
Agbaje, Andrew O; Saner, Christoph; Zhang, Jie; Henderson, Mélanie; Tuomainen, Tomi-Pekka
Journal of clinical endocrinology and metabolism , 109 , e1708-e1719
Inflammation: reviewing current evidence
Agbaje, Andrew O
TYÖTERVEYSLÄÄKÄRI , 42 , 44-47
2023
Associations of Sedentary Time and Physical Activity From Childhood With Lipids: A 13-Year Mediation and Temporal Study
Agbaje, Andrew O
Journal of clinical endocrinology and metabolism , 109 , e1494-e1505
Effects of accelerometer-based sedentary time and physical activity on DEXA-measured fat mass in 6059 children
Agbaje, Andrew O; Perng, Wei; Tuomainen, Tomi Pekka
Nature communications , 14
Longitudinal Mediating Effect of Fat Mass and Lipids on Sedentary Time, Light PA, and MVPA with Inflammation in Youth
Agbaje, Andrew O
Journal of clinical endocrinology and metabolism , 108 , 3250-3259
A 7-year longitudinal association of total cholesterol with premature structural and functional cardiac damage progression in youth: the ALSPAC birth cohort study
Agbaje, Andrew O
European heart journal
An average of 60mins/day of moderate to vigorous physical activity from childhood through young adulthood was associated with worsening cardiac structural damage in youth: A 13-year longitudinal study
Agbaje, Andrew O
European heart journal abstract
Cumulative accelerometer-based light physical activity from childhood through young adulthood progressively decreases left ventricular mass in British youth: a 13-year longitudinal study
Agbaje, Andrew O
European heart journal
Cumulative accelerometer-based light physical activity from childhood through young adulthood with arterial stiffness and carotid intima-media thickness progression: a 13-year longitudinal study
Agbaje, Andrew O; Barker, Anna; Lewandowski, Adam James; Leeson, Paul; Tuomainen, Tomi-Pekka
European heart journal
Cumulative accelerometer-based sedentary time from childhood through young adulthood with increased arterial stiffness and carotid intima-media thickness in youth: a 13-year longitudinal study
Agbaje, Andrew O; Barker, Anna; Lewandowski, Adam James; Leeson, Paul; Tuomainen, Tomi-Pekka
European heart journal
Cumulative accelerometer-based sedentary time from childhood through young adulthood with progressive left ventricular remodelling in British youth: a 13-year longitudinal study
Agbaje, Andrew O
European heart journal
Increased triglyceride independently associates with premature structural and functional cardiac damage progression in asymptomatic adolescents: a 7-year longitudinal study
Agbaje, Andrew O
European heart journal
Prospective associations of non-HDL cholesterol with premature structural and functional cardiac damage progression in British youth: the ALSPAC study
Agbaje, Andrew O
European heart journal
Longitudinal Associations of Accelerometer-Based Sedentary Time and Physical Activity With Blood Pressure Progression From Childhood Through Young Adulthood: A 13-year Mediation and Isotemporal Substitution Study of 2513 Children
Agbaje, Andrew O
Circulation
Arterial stiffness but not carotid intima-media thickness progression precedes premature structural and functional cardiac damage in youth: A 7-year temporal and mediation longitudinal study
Agbaje, Andrew O; Zachariah, Justin P; Tuomainen, Tomi-Pekka.
Atherosclerosis , 380
Suppressing effect of HDL-cholesterol on the associations of accelerometer-based sedentary time with low-grade inflammation: A 13-year longitudinal study from childhood through young adulthood
Agbaje, Andrew O
Atherosclerosis
Cumulative effect of accelerometer-based moderate-to-vigorous physical activity from childhood through young adulthood on carotid intima-media thickness progression: The ALSPAC birth cohort study
Agbaje, Andrew O
Atherosclerosis
Adolescents cholesterol passport: a universal pediatric lipid screening tool to combat atherosclerosis—the world's deadliest scourge
Agbaje, Andrew O
Frontiers in pediatrics , 11
Adolescents cholesterol passport: a universal pediatric lipid screening tool to combat atherosclerosis—the world's deadliest scourge
Agbaje, Andrew O
Frontiers in pediatrics , 11 , . 1228483
Arterial Stiffness Preceding Metabolic Syndrome in 3862 Adolescents: A Mediation and Temporal Causal Longitudinal Birth Cohort Study
Agbaje, Andrew O
American journal of physiology : heart and circulatory physiology , 324 , H905-H911
Does arterial stiffness mediate or suppress the associations of blood pressure with cardiac structure and function in adolescents?
Agbaje, Andrew O
American journal of physiology : heart and circulatory physiology , 324 , H776-H781
Associations of accelerometer‐based sedentary time, light physical activity, and moderate‐to‐vigorous physical activity with resting cardiac structure and function in adolescents according to sex, fat mass, lean mass, BMI, and hypertensive status
Agbaje, Andrew O
Scandinavian journal of medicine and science in sports , 33 , 1399-1411
Longitudinal Left Ventricular Mass Indexing for DEXA-Measured Lean Mass and Fat Mass: Normative Reference Centiles in Post-Pubertal Adolescents and Young Adults
Agbaje, Andrew O
American journal of physiology : heart and circulatory physiology , 324 , H571-H577
Cumulative insulin resistance and hyperglycaemia with arterial stiffness and carotid IMT progression in 1779 adolescents: A 9-Year Longitudinal Cohort Study
Agbaje, Andrew O; Zachariah, Justin P; Bamsa, Olutola; Odili, Augustine N; Tuomainen, Tomi-Pekka
American journal of physiology : endocrinology and metabolism , 324 , E268-E278
Temporal longitudinal associations of carotid-femoral pulse wave velocity and carotid intima-media thickness with resting heart rate and inflammation in youth
Agbaje, Andrew O; Barmi, Samuel; Sansum, Kate M; Baynard, Tracy; Barker, Alan R; Tuomainen, Tomi-Pekka
Journal of applied physiology , 134 , 657-666
Elevated Blood Pressure and Worsening Cardiac Damage During Adolescence
Agbaje, Andrew O
Journal of pediatrics , 257
Cumulative dyslipidemia with arterial stiffness and carotid IMT progression in asymptomatic adolescents: A simulated intervention longitudinal study using temporal inverse allocation model
Agbaje, Andrew O.; Lloyd-Jones, Donald M.; Magnussen, Costan G.; Tuomainen, Tomi-Pekka
Atherosclerosis , 364 , 39-48
2022
Cardiorespiratory Fitness in Adolescence: A Telescope into Future Cardiovascular Health
Agbaje, Andrew O
European journal of preventive cardiology , 30 , 404-406
Cumulative muscle mass and blood pressure but not fat mass drives arterial stiffness and carotid intima-media thickness progression in the young population and is unrelated to vascular organ damage
Agbaje, Andrew O.; Barker, Alan R.; Tuomainen, Tomi-Pekka
Hypertension research , 46 , 984-999
To prevent hypertension in Africans: do we need to eat more vegetables?
Agbaje, Andrew O
European journal of preventive cardiology , 29 , 2333–2335
Cumulative dyslipidaemia from mid-adolescence through young adulthood with carotid intima-media thickness progression: a 9-year longitudinal study
Agbaje, Andrew O; Lloyd-Jones, D M; Magnussen, C G; Tuomainen, T P
European heart journal
Cumulative hyperinsulinemia, hyperglycaemia, and insulin resistance from mid-adolescence through young adulthood with carotid intima-media thickness progression: a 9-year longitudinal study
Agbaje, Andrew O; Zachariah, J P; Bamsa, O; Odili, A N; Tuomainen, T P
European heart journal
Does arterial stiffness progression temporally precede higher low-grade inflammation in adolescents? Causal longitudinal evidence using auto-regressive cross-lagged structural equation models
Agbaje, Andrew O; Barmi, S; Sansum, K M; Baynard, T; Barker, A R; Tuomainen, T P
European heart journal
Longitudinal associations of cumulative dyslipidaemia from mid-adolescence through young adulthood with arterial stiffness progression: the ALSPAC study
Agbaje, Andrew O; Lloyd-Jones, D M; Magnussen, C G; Tuomainen, T P
European heart journal
Simulated intervention and optimal timing for attenuating dyslipidaemia-related atherosclerotic progression in the young: a temporal inverse allocation analysis of the ALSPAC cohort
Agbaje, Andrew O; Lloyd-Jones, D M; Magnussen, C G; Tuomainen, T P
European heart journal
Temporal causal longitudinal associations of high-sensitivity C-reactive protein with carotid intima-media thickness progression in adolescents: the ALSPAC birth cohort study
Agbaje, Andrew O; Barmi, S; Sansum, K M; Baynard, T; Barker, A R; Tuomainen, T P
European heart journal
Arterial stiffness precedes hypertension and metabolic risks in youth: a review
Agbaje, Andrew O
Journal of hypertension , 40 , 1887-1896
Mediating role of body composition and insulin resistance on the association of arterial stiffness with blood pressure among adolescents: The ALSPAC study
Agbaje, Andrew O
Frontiers in cardiovascular medicine , 9 , 939125
Cumulative dysglycemia, hyperinsulinemia and insulin resistance with arterial stiffness progression in healthy adolescents: The Avon Longitudinal Study of Parents and children (ALSPAC)
Agbaje, AO.
Atherosclerosis
Adolescence arterial stiffness precedes elevated blood pressure in young adulthood: The ALSPAC birth cohort
Agbaje, Andrew O; Barker, Alan R; Tuomainen, Tomi-Pekka
Metabolism: clinical and experimental
Fat mass paradox and carotid intima-media thickness progression: A longitudinal study from childhood through young adulthood
Agbaje, Andrew O; Barker, Alan R; Tuomainen, Tomi-Pekka
Metabolism: clinical and experimental
Longitudinal and bi-directional associations of arterial stiffness with general and central fat mass from adolescence through young adulthood: The ALSPAC Study
Agbaje, Andrew O; Barker, Alan R; Tuomainen, Tomi-Pekka
Metabolism: clinical and experimental
Effect of Arterial Stiffness and Carotid Intima-Media Thickness Progression on the Risk of Dysglycemia, Insulin Resistance, and Dyslipidemia: a Temporal Causal Longitudinal Study
Agbaje, Andrew O; Barker, Alan R; Mitchell, Gary F; Tuomainen, Tomi-Pekka
Hypertension , 79 , 667-678
2021
Effects of Arterial Stiffness and Carotid Intima-Media Thickness Progression on the Risk of Overweight/Obesity and Elevated Blood Pressure/Hypertension: a Cross-Lagged Cohort Study
Agbaje, Andrew O; Barker, Alan R; Tuomainen, Tomi-Pekka
Hypertension , 79 , 159-169
A 7-Year Arterial Stiffness and Carotid Intima-Media Thickness Progression Predict Obesity, High Lean Mass, and Incident Hypertension from Age 17.7 to 24.5 Years: the ALSPAC Study
Agbaje, Andrew O; Barker, Alan R; Tuomainen, Tomi-Pekka
Circulation , 144
Differing Relations Of Arterial Stiffness And Carotid Intima-Media Thickness In Adolescence With Metabolic Risks In Young Adulthood: The ALSPAC Study
Agbaje, Andrew O; Barker, Alan R; Tuomainen, Tomi-Pekka
Circulation , 144
Adiponectin and lean mass in relation to endothelial function, arterial elasticity and arterial stiffness in 9-11-year-old-the ALSPAC study
Agbaje, Andrew O; Barker, A R; Tuomainen, T-P
Pediatric diabetes
Arterial stiffness in adolescence predicts elevated blood pressure in young adulthood: the ALSPAC study
Agbaje, Andrew O; Barker, A R; Tuomainen, T-P
European heart journal , 42
Associations of endothelial function, arterial elasticity, and arterial stiffness with adiponectin and skeletal muscle mass
Agbaje, Andrew O; Barker, Alan R; Tuomainen, Tomi-Pekka
International journal of epidemiology , 50
Arterial stiffness and carotid intima-media thickness in relation to cardiometabolic health in adolescence: The ALSPAC study
Agbaje, Andrew O; Barker, A R; Tuomainen, T-P
Atherosclerosis , 331
A 15-year Cumulative High Exposure to Lean Mass and Blood Pressure but not Fat Mass predicts the 7-year change in Carotid-Femoral Pulse Wave Velocity and Carotid Intima-Media Thickness: The ALSPAC study
Agbaje, Andrew O; Barker, Alan R; Tuomainen, Tomi-Pekka
Circulation , 143
Longitudinal associations of fat mass, lean mass, body mass index and blood pressure from childhood through young adulthood with carotid-femoral pulse wave velocity and carotid intima-media thickness at age 24.5 years
Agbaje, Andrew O; Barker, Alan R; Tuomainen, Tomi-Pekka
Journal of the american college of cardiology , 77
Association of Fat Mass, Lean Mass, Body Mass Index, and Blood Pressure with Carotid-Femoral Pulse Wave Velocity and Carotid Intima-Media Thickness in Young Adults: The ALSPAC study
Agbaje, Andrew O; Barker, Alan R; Tuomainen, Tomi-Pekka
Metabolism: clinical and experimental , 116
Association of carotid-femoral pulse wave velocity and carotid intima-media thickness with cardiometabolic risks among young adults: The Alspac study
Agbaje, Andrew O; Barker, A R; Tuomainen, T-P
Atherosclerosis , 331
Cardiorespiratory Fitness, Fat Mass, and Cardiometabolic Health with Endothelial Function, Arterial Elasticity, and Stiffness in Children
Agbaje, Andrew O; Barker, Alan R; Tuomainen, Tomi-Pekka
Medicine and science in sports and exercise , 54 , 141-152